The eighth edition of the Indian Super League (ISL) 2021-22, has recently commenced. Amongst the 11 participating teams, the defending champions of the ISL are Mumbai City FC.
In the earlier season, Mumbai City FC won the league as well as the ISL trophy after beating ATK Mohun Bagan in the final. The schedule of Mumbai City FC in this edition can be looked at as below:
| Date | Game | Time | Venue |
| November 27 | Mumbai City FC vs Hyderabad FC | 21:30 | PJN Stadium, Fatorda |
| December 01 | ATK Mohun Bagan vs Mumbai City FC | 19:30 | PJN Stadium, Fatorda |
| December 04 | Bengaluru FC vs Mumbai City FC | 21:30 | Athletic Stadium, Bambolim |
| December 09 | Mumbai City FC vs Jamshedpur FC | 19:30 | PJN Stadium, Fatorda |
| December 15 | Mumbai City FC vs Chennaiyin FC | 19:30 | PJN Stadium, Fatorda |
| December 19 | Mumbai City FC vs Kerala Blasters FC | 19:30 | PJN Stadium, Fatorda |
| December 27 | NorthEast United FC vs Mumbai City FC | 19:30 | PJN Stadium, Fatorda |
| January 3 | Odisha FC vs Mumbai City FC | 19:30 | Tilak Maidan Stadium |
| January 7 | SC East Bengal vs Mumbai City FC | 19:30 | Tilak Maidan Stadium |
In the opening game of Mumbai City FC's match against FC Goa, on Monday, November 22, Mumbai beat its opponent by 3-0, with goals from Igor Anguloa and Ygor Catatau.
Additionally, fans are of the opinion that it is too early to proclaim that the team will defend the title since certain changes were made to the squad. According to them, however, the amalgamation of experienced and young players with the intent to stick together and style of play could help them achieve the feat.
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